 |
Human CellExp CD23, human recombinant |
中文名称 |
【CD23】人源细胞表达的重组人CD23(50 ug) |
供应商 |
BioVision |
产品货号 |
7435-50 |
产品报价 |
客服1: 客服2: |
购买方式
|
银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系010-52406250. |
产品新闻 |
微信号:AD-Bio |
订阅号: Bio-888 |
技术微信:hugasis |
销售微:ex-2008 |
 |
 |
 |
 |
|
背景资料 |
Cluster of differentiation 23 (CD23), also known as Low affinity immunoglobulin epsilon Fc receptor (FCER2), C-type lectin domain family 4 member J (CLEC4J), Fc-epsilon-RII (FcεRII), Immunoglobulin E-binding factor (IGEBF), is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. CD23 is known to have role of transportation in antibody feedback regulation. Antigen that enters the blood stream is captured by antigen specific IgE antibodies. The IgE immune complexes that are formed bind to CD23 molecules on B cells, and are transported to the B cell follicles of the spleen. The antigen is then transferred from CD23+ B cells to CD11c+ antigen presenting cells. The CD11c+ cells in turn present the antigen to CD4+ T cells, which can lead to an enhanced antibody response. In flow cytometry, CD23 is helpful in the differentiation of chronic lymphocytic leukemia (CD23-positive) from mantle cell leukemia (CD23-negative). |
产品描述 |
该人源细胞表达的重组人CD23产品为冻干形式.具体样式见英文说明:Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
来源宿主 |
提供的【CD23】人源细胞表达的重组人CD23产品的来源为人胚肾HEK293细胞重组表达重组表达. |
序列 |
人源细胞表达的重组人CD23蛋白产品,又称FCER2; FCER-2; CD23; CD-23; CD23A; CD-23A; CLEC4J
; FCE2; FCE-2; IGEBF; FcεRII; FcεRⅡ; Fc epsilon RII.其对应NCBI基因号为2208,对应
Accession号为P06734.
|
溶解建议 |
人源细胞表达的重组人CD23产品请按照说明书建议进行溶解操作:Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
保存建议 |
在您收到发出的【CD23】人源细胞表达的重组人CD23产品后,建议将其置于-20°C保存. |
产品说明书 |

|
精品推荐:
产品名称 |
规格 |
操作手册 |
货号 |
询价 |
RNA甲基化极易定量检测试剂盒(荧光法) |
96次 |
英文PDF-中文PDF |
A-P-9009-96 |
 |
RNA甲基化极易定量检测试剂盒(荧光法) |
48次 |
英文PDF-中文PDF |
A-P-9009-48 |
|
总组蛋白H3K27乙酰化定量检测试剂盒(比色法) |
48次 |
PDF |
A-P-4059-48 |
|
总组蛋白H3K27乙酰化定量检测试剂盒(比色法) |
96次 |
PDF |
A-P-4059-96 |
|
EpiNext 高灵敏重亚硫酸盐测序试剂盒(Illumina) |
12次 |
PDF |
A-P-1056A-12 |
EpiNext 高灵敏重亚硫酸盐测序试剂盒(Illumina) |
24次 |
PDF |
A-P-1056A-24 |
 |
96孔DNA甲基化极速修饰试剂盒(磁珠法) |
96次 |
英文PDF-中文PDF |
A-P-1050-096 |
|
96孔DNA甲基化极速修饰试剂盒(磁珠法) |
192次 |
英文PDF-中文PDF |
A-P-1050-192 |
|
抗人C5a/C5a desArg单克隆抗体(克隆号2942) |
100ug |
|
C-HM2078 |
|
抗人TNF-R II单克隆抗体(克隆号80M2),FITC标记 |
100ug |
|
C-HM2022F |
|
抗人TNF-R II单克隆抗体(克隆号MR2-1),生物素标记 |
50ug |
|
C-HM2008 |
|
抗人TNF-R I单克隆抗体(克隆号MR1-2),生物素标记 |
50ug |
|
C-HM2006 |
|
抗小鼠TREM-2单克隆抗体(克隆号6E9) |
100ug |
PDF |
C-HM1129F |
 |
m6A RNA甲基化定量检测试剂盒(比色法) |
96 次 |
英文PDF--中文PDF |
A-P-9005-96 |
|
RNA甲基化修饰试剂盒 |
50 次 |
英文PDF--中文PDF |
A-P-9003-050 |
|
EZ RNA甲基化修饰试剂盒 |
50 次 |
英文PDF--中文PDF |
A-R5001 |
|
表观遗传学产品全面解决方案列下:
推荐阅读:
关于5-hmC
5-hmC是近年来在动物组织中发现的,由胞嘧啶修饰而来。5-hmC在表观遗传学上的功能可能与5-甲基化胞嘧啶(5-mC)不同。尽管到现在为止还不确知其功能,有研究者猜测它在调控基因的表达与关闭过程中起着重要的作用。5-mC的发现让我们不得不重新评估DNA甲基信息,也不得不监测人类的健康组织和病理组织之间5-mC相对分布的差异。在EPI公司的MethylFlash技术之前,我们还没有发现任何直接的常规方法来检测5- hmC,以及区分5-hmC和5-mC
5-hmC 和 5-mC的区别
时下常用的DNA甲基化分析方法包括限制内切酶酶切和亚硫酸氢盐或MeDIP介导的MS-PCR和测序,这些技术都不适合用来检测5-hmC,因为它与5-mC事实上很难用这类方法区分开来。为了解决这个问题,EPIk研制了MethylFlash羟甲基化DNA定量试剂盒(荧光法)。本试剂盒提供了一种很经济的方法来检测5-羟甲基化胞嘧啶,并且区分5-hmC, 5-mC, 和 C,使得研究者能够重新评估他们的DNA甲基化信息,也能够在新样品中寻找DNA羟甲基化。 |