SARS-CoV-2 IgM/IgG 抗体检测试剂盒 货号：A-D-1001
SeroFlash SARS-CoV-2 IgM/IgG Antibody Detection Kit
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背景资料：In the process of pathogenic microorganism infection, IgG and IgM are the most commonly used antibody markers of infectious diseases. IgM, as the first antibody in the process of infection, is usually used as a marker of acute infection. With the development of infection, IgM concentration gradually decreases and disappears after the appearance of IgG. IgG usually exists in the body for a long time, even if the virus has been completely eliminated. Positive blood can be used as an indicator of infection and previous infection. Therefore, detecting SARS-CoV-2 IgG and IgM antibodies is of great clinical significance and could effectively control large-scale transmission of SARS-CoV-2。
产品描述：This kit uses lateral flow colloidal gold-based immunassay technology by spraying colloidal gold-labeled recombinant SARS-CoV-2 antigen and a control antibody gold marker on a binding pad. Two test lines, G and M, and a control line C on the membrane are coated with mouse anti-human IgG (G), mouse anti-human IgM (M), and a quality control antibody (C), respectively. The M line is used to test for SARS-CoV-2 IgM antibody, the G line is used to test for SARS-CoV-2 IgG antibody, and the C line is used to check if the sample has been added to the sample hole of the test card. The sample will subsequently move along the test card under the action of chromatography. If the sample contains SARS-CoV-2 IgG or IgM antibodies, the antibodies bind to the gold-labeled virus antigen. The immune complex forms a sandwich complex with the coated anti-human IgG or IgM monoclonal antibody at the G or M line, showing colored bands accordingly, and indicates positive IgG or IgM antibodies for SARS-CoV-2. If the test line G and M do not produce color, then a negative result is displayed。
起始材料：This assay is suitable for human serum, plasma, whole blood, or fingertip blood
产品特点：
1·Rapid Method: Obtain results within 15 minutes without special instrumentation；
2·Zero Sample Prep: Detection directly from whole blood or serum, as well as fingertip blood samples；
3.Two-In-One: Both IgG and IgM antibodies are simultaneously detected for additional confirmation, saving on costs versus other methods that detect them separately.
4.High Sensitivity: 97.8% positive test correlation for IgM antibodies in patients with an infection window of 11-24 days; Total approximate accuracy of both positive and negative correlation with IgG and IgM signals is 92%；
5.High Specificity: 100% negative correlation without cross-reactivity to other human coronaviruses, influenza A/B viruses, and many other viruses*；
6.Early Detection Window of IgM: Antibodies can be detected in as early as four days while symptomatic。
This product is manufactured under ISO 9001:2015 and ISO 13485:2016 standards, and meets the provisions of the EC Council Directives (In Vitro Diagnostic Medical Devices DIRECTIVE 98/79/EC).
数据分析：
| 标准曲线展示 |
标曲分析 |
 |
 |
| 使用m6A甲基化酶活性/抑制分析试剂盒(比色法) 针对重组的METTL3/14 完成了m6A 甲基化酶活性的检测.重组的人类METTL3/14酶在不同浓度下的数据. |
用m6A甲基化酶分析标准品生成标准曲线 |
参考文献：
1.Lewinska A et. al. (February 2017). Downregulation of Methyltransferase Dnmt2 Results in Condition-dependent Telomere Shortening and Senescence or Apoptosis in Mouse Fibroblasts. J Cell Physiol.
保存建议：在接收到艾德寄出的试剂盒后请按照说明书建议，使用不同的保存条件或温度来保存试剂盒内组分。
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