【Exendin 4】重组醋酸艾塞那肽 货号：C-HOR-269
Recombinant Exendin-4
背景资料：Exedin-4 Recombinant is a glucagon like peptide-1 receptor agonist. The native hormone is produced in the gut of Gila monster Heloderma suspectrum (a type of reptile found in the desert) that stimulates insulin production without causing threateningly low blood sugar, which can occur after using insulin and some anti-diabetes products. Recently, researchers used extracted saliva from gila monsters to create an unprecedented breakthrough in Diabetes Type 2 treatment. Unlike other products taken for type 2 diabetes, Exedin-4 has not been linked with weight gain and actually resulted in weight loss, according to the researchers. Exedin-4 enhances glucose-dependant insulin secretion, suppresses inappropriately elevated glucagon secretion and slows gastric emptying in vivo. It also promotes B-cell proliferation and neogenesis in vitro and in animal models. Exedin-4 stimulates an increase in acinar cAMP, without stimulating the release of amylase.
产品描述：Exendin-4 Recombinant is a novel 39-amino acids peptide having a molecular mass of 4186.7 Dalton, which shares 53%, sequence homology with GLP-17-36 amide and interacts with the same membrane receptor. The Exendin-4 is purified by proprietary chromatographic techniques.
来源宿主:大肠杆菌中重组表达
序列:His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser.
溶解建议:Sterile Filtered White lyophilized (freeze-dried) powder. The Exendin-4 peptide was lyophilized after extensive dialyses against 20mM PBS and contains 4% mannitol. It is recommended to reconstitute the lyophilized Exendin Recombinant in sterile 18MΩ-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
保存建议：Lyophilized Exendin Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution Exendin-4 should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
定购信息：
| 产品名称 |
规格 |
操作手册 |
货号 |
询价 |
| 【Exendin 4】重组醋酸艾塞那肽 |
20 ug |
PDF |
C-HOR-269-1 |
 |
| 【Exendin 4】重组醋酸艾塞那肽 |
100 ug |
PDF |
C-HOR-269-2 |
|
| 【Exendin 4】重组醋酸艾塞那肽 |
1 mg |
PDF |
C-HOR-269-3 |
|
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